1) Atorvastatin & Simvastatin
Intermediate 
A)
(4R-cis)-1,1-dimethyl
ethyl-6-{2[2(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylamino-
carbonyl)]-1H-pyrrol-1-yl}ethyl-2,2-dimethyl-1,3-dioxane-4-acetate
B)
(4R-cis)-1,1-dimethyl
ethyl-6-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylamino-
carbonyl)]-1H-pyrrol-1-yl}ethyl-2,2-dimethyl-1,3-dioxane-4-acetate
C)
(4R-cis)-t-butyl-6-Cyanomethyl -2,2-dimethyl-1,3-dioxane-4-acetate
[125971-94-0]
D)
(4R-cis)-t-butyl-6-(2-amino methyl)-2,2-dimethyl-1,3-dioxane-4-acetate [125995-13-3]
E)
tert-butil(2R,5R)-7-amino-3,5-o-isopropyliden-3,5-dihydroxy
heptanoate
F)
4-Fluoro-A-[2-Methyl-L-oxopropy]-gama-oxo-N,beta-diphenyl Benzene ButaneAmide
G)
4-(4-fluorophenyl)-2-isobutyryl-4-oxo-N,3-diphenyl butan amide[CAS N.
125971-96-2]
H)
Ethyl(R)-(-)-Cyano-3-hydroxy butyate [ CAS No.
141942-85-0]
K) (R)-4-Cyano-Hydrobutyric ACid Ethyl Ester
M)
3-Ethyl-5-(2-Hydroxyethyl)-4-Methylthiazolium
Bromide [#54016-70-5]
N)
4-METHYL-3-OXO-N-PHYNYL-2-(PHYNYLMETHYLENE)PENTANAMIDE
2)Clopidogrel &
Ticlopidine intermediate
A) 2-Thiophene Ethylamine /
2-Thiophene Ethanol / 2-Thiophen Carboxaldehyde
B) a-Bromo-(2-Chloro)phenyl Acetic
Acid
C) Methyl-alfa-amino-o-chloro phenyl
acetate
D) (S)-(2-chlorophenyl)glicine methyl
ester
E)
DL-Alfa-2-chloro-Phenyl Glycine
F) 2-(2-CHLORO PHENYL) GLYCINE 99% MIN
(CAS NO: 88744-36-9)
G) D-(+)-Methyl
alpha-(2-thienylethamino)-2-chlorophenyl)acetate
H) 2-Chloro
Benzylamine ( for Ticlopidine )
3) Glimepiride
intermediate
a)
3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one
b)
Trans-4-methyl-Cyclohexyl Isocyanate
c)
Trans-4-methyl-Cyclohexylamine
d)
N-(2-[4-(Amino sulfonyl)
Phenyl]ethyl)-3-ethl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-Carboxamide
e)
3-Ethyl-4-Methyl-2-oxo-N-(2-p-chlorosulphonyl
phenylethyl)-3-pyrrolin-1-Carboxamide
f) Phenylethyl
Isocyanate
4) Finasteride Intermediates
:
a)
4-aza-androstan-3-one- 17 beta carboxylic acid or carboxylic acid methyl
ester
b)
4-aza-androst-5-en-3-one- 17 beta carboxylic acid or carboxylic acid methyl
ester
c) androst-4-ene-3-one -17
beta carboxylic acid or carboxylic acid methyl ester[302-97-6]
d)
ANDROST-4-AZA-3-ONE-17BETA-N-TERT¡ªBUTYL
CARBOXAMIDE [98319-24-5]
5) Ganciclovir + Famciclovir + Valaciclovir +
Penciclovir intermediate
a) Diacethy
guanine ( Guanine)
b)
Tripropanoxy Glycerol
c)
1,3-diacetoty-2-(acetoty methoxy)-propane ( side chain
)
d)
N2-acetyl-o,o'-diacetoty ganciclovir (
diprotection ganciclovir)
e) 1,3 DIOXALANE
DIACETATE 099% MIN.
f) 2,9
DIACETYL GUANINE
g)
9-(Acetoxy ethoxy methyl)Guanine acetate
h) 5-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxane (for Famciclovir)
6) Raloxifene
Intermediates :
a)6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophene
b)4-methoxy
phenacyl Bromide [CAS 500-65-7]
c)4-(2-Piperidionethoxy)benzoic acid [500-65-7]
d)3-METHOXY
THIOPHENOL
7) Terbinafine HCL Intermediates
a)
Methyl-Naphthane 1-yl-Methylamine
b)
3,3'-Dimethyl-1-Butyne {CAS 917-92-0}
c)
Trans-1,3-Dichloro propylene
8) Carvedilol
Intermediates:
A)2-(2-MethoxyPhenoxy)
ethylamine HCL
B
)9-Methyl-1,2,3,4-tetrahydro-4-Oxocarbazole
C)4-Hydroxy Carbazole
D)4-(2,3-Epoxypropoxy)-Carbazole
10) PAROXETINE +
FLUOXETINE intermediates
A) 3,4-(methylenedioxy)phenol (sesamol)
B) (-)-4-(4-fluorophenyl)-3-hydroxy methyl-N-methyl-Piperidine
C)
(-)-4-(4-fluorophenyl)-3-[3,4-methylenedioxyphenyl)oxymethyl]-N-methyl
piperidine
D) 4R-(4`-Fluorophenyl)-3S-[(3`,4`-Methylenedioxhyphenoxyl)Methyl]-1-Methylpiperidine
E) 4-BROMO
FLUORO BENZENE [ 460-00-4 ]
F) N,N-DIMETHYL
AMINO PROPIOPHENE-3-ONE HYDROCHLORIDE ( for Fluoxetine)
G) N-METHYL-N-CARBETHOXY-3-[4-(TRIFLUOROMETHYL)PHYNOXY]BENZENEPROPYL
AMINE
11)
BETAMETHASONE intermediates
1)
17alpha,21-dihydroxy-16beta-methyl-9beta,11beta-epoxy-pregna-1,4-diene-3,20-dione
2) Pregna-1,4,9-triene-3,20-dione-16alpha-methyl-17alpha,21-dihydroxy-
12) Losartan & Irbesartan & Candesartan
& Valsartan:
A)
5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)tetrazole
B) 2-Cyano-4-methyl biphenyl
C)
2-Butyl-4-chloro-5-Formylimidazole [CAS NO: 83857-96-9]
D)
4,4-Dimethyl-2-(2'-Methoxyphenyl)-Oxazoline
E) 2-Cyano-4-Bromo methyl
biphenyl ( for
Losartan)
F)
2-butyl-1,3-diazapira[4,4]non-1-en-one (for
Losartan)
G)
2n-Butyl-4-Spirocyclopentane-2-imidazolin-5-one ( for
Irbesartan)
H)
1-[(2-Cyclobiphenyl-4-yl)methyl]-2-n-buthyl-4-spirocyclopentane-2-imidazole
-5-one
K) N-Triphenylmethyl-5-(4`-Methylbiphenyl)-2-Tetrazole(Intermediate of
Losartan)
L) 1-AMINO
CYCLOPENTANACETAMIDE ( for Irbesartan)
13) Clinafloxacin+ Tosufloxacin + Enrofloxacin
intermediate
a) 3-amino-pyrrolidine Dihyrdochloride
[103831-11-4] //
Pyrrolidine
b) Ethyl -(2,6-dichloro-5-fluoro-nicotinoyl) acetate
c) 2,6-dichloro-5-fluoro-micotinoyl-acetate
d)
2,6-dichloro-5-fluoro-Nicotinic Acid
e)
2,4-dichloro-5-fluoro-acetophenone
14) Quinapril + Benazepril + Lisinopril+
Enalapril
a) (S)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid,
Phenylmethyl Ester, 4-
Methylbenzene Sulfonate (for Quinapril)
b) D-3-Acetylthio-2-Methylpropionyl-L-Proline ( Captopril)
c) N-[1-(S)-Ethoxycarbonyl-3-Phenylpropyl]-L-Alanine(ECPPA)
d)N2-[(1s)-Ethoxycarbonyl-3-Phenylpropyl]-N8-Trifluoroacetyl-L-Lysyl-L-Proline(
for Lisinopril)
f) T-Butyl,3S-Amino-2,3,4,5,-Tetrahydro-1H-[1]Benazepin-2-One-1-Acetate (
for Benazepril)
15 )Doxazoxin/Prazosin/Terazosin
Intermediates
a) 4-Amino-2-Chloro-6,7-Dimethoxy
Quinazoline CAS# 23680-84-4 (for
Doxazosin/terazosin)
b)
6,7-Dimethoxy -2,4(1H,3H)-quinazolinedione [28888-44-0]
c)1,2-Benzisothiazolin-3-one
d)
1,4-Benzodioxan-2-carboxic acid (for Doxazosin)
e)
2,4-dichloro-6,7-dimethoxy quinazoline
f)
N-(1,4-Benzodioxane-2-carbonyl) Piperazine (for Doxazosin )
16)Nelfinavir / Indinavir
Intermediates
a) 3-Acetoxy-2-methyl benzoic acid
b)
3-Acetoxy-2-methyl benzoyl chloride
c)
S-PHENYL-L-CYSTEINE [CAS 34317-61-8]
d)
R)-(-)GLYCIDYL BUTYRATE
17)
Gatifloxacin & Moxifloxacin
Intermediates
a) N-1
(1-ciclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinexarboxylic
acid
b) N-1
(1-ciclopropyl-6-fluoro-7-chloro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinexarboxylic
c)
7- amino-1-ciclopropyl- 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic
acid
d) 4-amino (or
4-nitro)-5-fluoro-2-chlorobenzoic acid
e)2,4-difluoro- 5-chloro-3-methoxy benzoic
acid
f) 2-fluoro-4,5-dichloro-3-methoxy
benzoic acid
h) 2,4,5-trifluoro-3-methoxy benzoic acid
18) Levofloxacin
Intermediates
a)
(s)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyridine[1,2,3-de][1,4]-benzoxazine-6-carboxylic
acid ( Levo Carboxylic )
b)
1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydro-quinoline-3-Carboxylic
acid
c) 2,3,4,5-Tetra fluoro benzoic acid
d) N-Methyl-Piperazine
19)Ceftriaxone & Cefixime & Cefuroxime Intermediate
a) Benzothiazole-2-(2-aminothiazole-4-yl)-(z)-2-methoxyimino
thioacetate
b) 1,2,4-triazin-2-methyl-6-hydroxy-3-thio-5-one
c) (z)-2-(tert-Butoxycarbouyl methoxyimino)-2-(2-aminothiazol-4-yl) Acetic acid
[TBCA]
d) syn-2-methoxy-imino-2-(2-furyl)-acetic acid,ammonium
salt [SMIA]
20) Pioglitazone
Intermediates
a) 2,
4-Thiazolidinedone
b)
5-ethyl-2-pyridinyl ethanol
c) 4-
hydroxy benzaldehyde
d)
[4-[2-(5-ethyl-2-pyridinyl) ethoxy] benzaldehyde
e)
5-[[4-[2-(5-ethyl-2-pyridinyl) ethoxy]
benzyldene]-2.4-thiazolidinedione
21) Tibolone
Intermediates :
a)7-alpha-methyl-5(10)-estrene-3,17-dione
b)7-alpha-methyl-3,3-dimethoxy
-5(10)-estrene-17-one
22 ) OLANZAPINE) //
2-Amino-3-Cyano-5-Methyl-thiophene
23)
DONAPEZIL) //
5,6-Dimethoxy Inden-1-one
24) SUMATRIPTAN ) //
4-Dimethylamino butyaldehyde dimethyl acetal
25
) NATEGLINIDE) //
trans-4-Isopropylcyclohexanecarboxylic acid
26) FLURBIPROFEN) //
4-Bromo-2-fluoro biphenyl
// 2-fluorobiphenyl
// 2-fluoroaniline
// 4-bromo-2-fluoroaniline
27) VENLAFAXINE)
// m(p-)-Methoxy Phenyl Acetonitrile
//
Amino p-methoxy phenyl cyclohexanol HCl
28) TIOCONAZOLE)
// 2-Chloro-3-Bromo-Methyl
Thiophene
29) (Sertraline) //
4-(3,4-dichlorophenyl)-1-tetrahydro-N-methyl-1-naphthalenamine
//
4-(3,4-Dichlorophenyl)-1-Tetralone
30) (Risedronate )
// 3-Acetyl
Pyridine
31) (Telmisartan
) //
2,3-Diamino-4-Carboxylic acid Toluene
// 2-Amino-4-Carboxylic acid Toluene
32) ( Rofecoxib) //
4-Methylthio Acetophenone
// 4-Methyl sulphonyl
Acetophenone
33) (Celecoxib
) //
4,4,4-trifluoro-1-[4-(methyl)phenyl]-butane-1,3-dione
// 4-sulphonamido phenyl hydrazine
hydrochloride
34) (Lansoprazole) //
2,3-Dimethyl-4-nitro-pyridin-N-oxide
// 2-Chloromethyl-3-methyl-4-(2,2,2-Fluoroethoxy) pyridine
Hydrochloride
35) (Fluconazole) //
2,4-difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
//
1-[2(2,4-DIFLUOROPHENYL)2-3,EPROXYPROPYL]1H-1,2,5-TRIAZOLE
// 1-[2(2,4-DIFLUOROPHENYL)2-3,EPROXYPROPYL]1H-1,2,4-TRIAZOLE
METHANESULPHONATE
// 1,3-DIFUORO BENZENE
// 1-Bromo-2,4-difluoro benzene
// 2-(3-amino-4-chlorobenyzoyl)-benzoic acid
36)
(Simvastatin)
// Tert Butyl Dimethyl
Chloro Silane
// 2,2-Dimethylbutyric acid
37) (Itraconazole) // a)
1-(4-Methoxyphenyl)piperazine. 2HCL
b)
Cis-[2(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl-methyl)-1,3-dioxalan-4yl]methyl methane
sulfonate
c)
2,4-Dihydro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
d) 1-((4-Methoxyphenyl)-4-1,
4-nitrophenyl)piperazine
e) 1-(4-AMINOPHENYL)-4-(4-METHOXY
PHENYL)PIPERAZINE
f) 2-bromo butane
38) KETOCONAZOLE )
//
cis-2-(2,4-dichlorophenyl)-2-(1H-Imidazole-1-yl-Methyl)-1,3-
dixoran-4-yl-methyl phenyl-methane
// 1-Acetyl-4(4-hydroxyphenyl)piperazine
// 2,2,4-trichloro acetophenone
39)
Pantoprazole) // 2-Chloromethyl-3,4-dimethoxy
pyridine Hcl [608-07-1]
//
5-difluoromethoxy-2-mercapto-1-H-benzimidazole[9763-62-7]
40) Loratadine
) //
N-methyl-4-chloro piperdine HCL
//
4-(3-ethyl[b-Chlorophenyl-piridine-2-Carboxy]-1-methyl Piperdine
//
2-Cyano,3[2(3,Chlorophenyl)] Ethyl Pyridine
//
2-Cyano-3-methyl pyridine
41) FLORPHENICOL) //
D-(+)-three-[1-(p-methyl-sulfonyl)phenyl]2-amino-1,3-prop-Anediol
42) Clonazepam +Diazepam) //
2-Amino-5-Nitro-2'-Chloro-Benzophenone
// 2-Amino-5,2-dichloro benzophenone
43) Ambroxoxl HCL) // Trans-4-Amino
Cyclohexanol
//
2-Amino-3,5-Dibromobenzaldehyde
44) Zaleplon ) //
3-Amino-4-Cyano-Pyrazole
// m-Acetamiacetophenone
// N-[3-(3-Dimethyl
amino-1-oxo-2-propenyl)phenyl]-N-ethylacetamide
//
N,N-Dimethyl Formaide dimethyl Acetal
45) Imiquimod )
// 4-Hydroxy-2-1H-Quinolinone
// 1,3-Dioxolane-2-pentanoic acid,
alfa-Amino-1H-Imidazo[4,5-c]
quinolinone,2-chloro-1-(2-methyl propyl)
46) Zafirlukast ) //
5-Nitroindole
// 3-Methoxy-4-Methyl Benzoic
Acid
//
5-(Bromomethyl)-3-methoxybenzoic acid, methyl
ester
//
2-methylbenzenesulphonamide
47)Ondanstron)
// n-Methyl -tetrahydro Carbazone
//
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbozol-4-one
48) Tamoxifene) // 2- Ethyl-1,2-diphenyl
ethanone
// 2-Ethyl Deoxy Benzoin
//
N,N-dimethyl-2-chloroethylamine HCL
//
2-dimethyl amino ethyl-4-bromo phenyl
ether
49) Zopiclone)
// 2,3-Pyrazinedicarboxylic
acid[CAS 89-01-0]
// 2-Amino-5-Chloro Pyridine
50) Melatonin)
// 5-methoxy tryptamine
[608-07-1]
51) LOXOPROFEN SODIUM) //
2-[(p-bromomethyl)phenyl] propionic acid
// 4-Bromomethylisophenyl Proponoic Acid
// 2-Ethoxycarbonyl Cyclopentanone
52) NIMESULPRIDE)
// Ethyl-2-oxo-4-phenyl butyrate
53) BUFLOMEDIL )
// 1,3,5-trimethoxy benzene
54) PRAZEPAM )
// Cyclo propyl
methanol
55) OMEPRAZOLE)
// 2,3,5-Trimethyl Pyridine
//
2-Mercapto-5-methoxy benzimidazole
// M-Chloro Peroxy Benzoic Acid
// 2-Chloromethyl-3,5-Dimethyl-4-Methoxy Pyridine Hcl
56) NAPROXEN
)
// 2-acetyl-6-methoxy naphthalene
57) ALLOPURINOL)
// Ethyl-3-aminopyrazol-4-carboxylate
58) METHOTREXATE)
// 4-(methylamino)-benzoic acid
// P-(2-methoxyethyl)-phenol
// 2,4,5,6-Tetra pyrimidine
59) MINOXIDIL
)
// 2,4-diamino-6-chloro pyrimdine
60) MICONAZOLE)
// 2-(2,4-dichloro benzyl)-2-Imidazole
ethanol
61) FUROSEMIDE )
// 2,4-dichloro-5-sulfamoyl
benzoic acid
//
4-chloro-3-sulfamonyl benzoic acid
62) PIROXICAM + MELOXICAM )
// 2-methyl-4-hydroxy-2H-1,2-benzothiamine-3-carboxylic
acid-isopropyl
(ethyl)ester-1,1-dioxide
//2-Amino-5-Methyl Thiazole CAS#41604-19-7
63) RIBAVIRIN
)
// Methyl-1H-1,2,4-trazole-3-Carboxylate
64) TRIMEBUTINE MALEATE)
// 3,4,5-thrimethoxy benzoic acid methyl ester [CAS#
118-41-2]
65) SULBUTAMOL ) //
N-(tert-butyl) benzylamine
// 4-Hydroxy acetophenone
// 2-(N-benzyl-N-tert-butylamino-4-hydroxy-3-hydroxymethyl
acetophenone
66) DICLOFENAC SODIUM) //
N-(2,6-dichloro phenyl) -Aniline
// 2-chloro phenyl acetic acid
// Indolinone
67) TRAMADOL
HCL) // 3-bromo Anisole
68) SILDENAFIL CITRATE) //
2-ethoxy-5-(4-methyl piperazine-1-yl-sulfonyl)benzoic acid
69) ETODOLAC )
// 2-ethyl phenyl hydrazine HCL
// Silitated 7-Ethyltryptophol
// 2,3-Dihydrofuran
70) TAZOBACTAM )
// a)
1H-1,2,3-triazole [288-36-8]
// b) Benzhydryl 6,6-dibromo
phenicillanate-1-oxide
// c) Benzhyxryl penicillanate-1-oxide
71) Ropivacaine
HCL) // L-Pipecolinic Acid
[3105-95-
72) Fenofibrate)
// 4-Hydroxy-4'-Chloro-Benzophenone
73) Bifonazole) //
Phenylbenzophenone
74) Sulindac)
// 5-Fluoro-2-Methyl-1-(4-Methylthiobenzylidene)Indene
75)
Amlodipine) //
Ethyl 4-Chloro Aceto Acetate
76) Bisoprolol)
// 4-Hydroxy Benzyl Alcohol
77) Nifedipine + Nicardipine + Nimodipine +
Nitrendipine
a)
2-Nitrobenzaldehyde
(for Nifedipine)
b)
3-Nitrobenzaldehyde (for
Nicardipine,Nimodipine )
c) Methyl
3-Aminocrotonate (for Nicardipine,Nitrendipine )
d) Isopropyl
3-Aminocrotonate (for Nimodipine )
e) 2-Methoxy Ethyl Aceto
Acetate (for Nimodipine )
f)
2-Methoxyethyl-2-(3-Nitrobenzylidene) Aceto Acetate ( for Nimodipine
)
78) Gliclazide
) //
N-Amino-3-Azabicyclo[3.3.0]octane Hcl
CAS#58108-05-7
79) Timolol)
// S-(-)-tert
Butylamino-1,2-Propanediol CAS# 30315-46-9
80) Haloperidol+Loperamide) //
4-(4-Chlorophenyl)-4-Hydroxypiperidine
81) Ipriflavone)
// 7-Hydroxyisoflavone
82) CIPROFLOXACIN) // 7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUORO-4-OXO-3-QUINOLINE CARBOXYLIC
ACID
83) GLICLAZIDE)
// 3-AZA
BICYCLO(3.3.0)OCTANE.HCL [5661-03-0 ]
// N-AMINO-3-AZA
BICYCLO(3.3.0)OCTANE.HCL [54528-00-6 ]
84)Other
Intermediates Series
a) FMOC Amino Acids
(FMOC-CL,FMOC-Onsu...20
types)
b) ommercial Indoles ,
Indoles, Imidazoles,
c) Purines, ,
Pyrimidines
d) New Thiophene intermediates
e) Prostaglandins ( PGE1 , PGE2)
3,3,5,5-Tetra Methyl Benzidine
2-Fluoro-5-Amino-Cyano
Benzene
2-(2-Aminoethoxy)-Anisole
1H,2H,3H-Tetra fluoro propanol
2-Chloro-3-Cyano-Pyridine
2,5-Dihydroxy-1,4-dithiane
5-dibenzyl-glycyl
sailicylamide
5-methoxy Indole
[1006-94-6] /5-Bromo Indole /4-Hydroxy Indole